BDBM11460 2,6,9-trisubstituted adenine derivative::2-N-(4-aminocyclohexyl)-6-N-benzyl-9-cyclopentyl-9H-purine-2,6-diamine::2-[TRANS-(4-AMINOCYCLOHEXYL)AMINO]-6-(BENZYL-AMINO)-9-CYCLOPENTYLPURINE::H717

SMILES N[C@H]1CC[C@@H](CC1)Nc1nc(NCc2ccccc2)c2ncn(C3CCCC3)c2n1

InChI Key InChIKey=JTVILUUAQWQWBK-IYARVYRRSA-N

Data  7 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11460   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Homo sapiens (Human))
Lawrence Berkeley National Laboratory

LigandPNGBDBM11460(2,6,9-trisubstituted adenine derivative | 2-N-(4-a...)
Affinity DataIC50:  48nMpH: 7.5 T: 2°CAssay Description:The enzyme was assayed with substrate GST-Rb in the presence of 10 uM ATP/[gamma-33P] ATP, and capturing the 33-P labeled reaction products on GSH-Se...More data for this Ligand-Target Pair